Community Structure in the United States House of Representatives

We investigate the networks of committee and subcommittee assignments in the United States House of Representatives from the 101st--108th Congresses, with the committees connected by ``interlocks'' or common membership. We examine the community structure in these networks using several methods, revealing strong links between certain committees as well as an intrinsic hierarchical structure in the House as a whole. We identify structural changes, including additional hierarchical levels and higher modularity, resulting from the 1994 election, in which the Republican party earned majority status in the House for the first time in more than forty years. We also combine our network approach with analysis of roll call votes using singular value decomposition to uncover correlations between the political and organizational structure of House committees.Comment: 44 pages, 13 figures (some with multiple parts and most in color), 9 tables, to appear in Physica A; new figures and revised discussion (including extra introductory material) for this versio

Five patients with oedema: written for the Wightman Prize in Clinical Medicine, 1962

This is an account of five patients seen in :. iards 21, 23 and 24 of the Royal Infirmary, Edinburgh; all the patients suffered from some form of oedema. The severity of the oedema varied greatly in the different patients, as did the factors responsible for its appearance. This account aims merely to recount the clinical histories, with special emphasis on the oedema, and to discuss the causes as revealed in each patient.In the interests of brevity and clarity, it has been necessary to omit some of the details of the history and clinical findings in each patient where they were not strictly relevant to the problem of oedema, but any details of special interest have also been included. Although this is intended primarily as a clinical account, the discussion of the pathogenesis of oedema in each patient must, as so often in medicine today, delve into mechanisms at a microscopic and even at a molecular level. At this level, the discussion runs the risk of either being too brief and dogmatic, or else too detailed and inconclusive; and at any level the discussion must inevitably be incomplete. Many of the theories of the pathogenesis of oedema are speculative and controversial, and the more complete the reading of the literature, the more confusing the picture becomes. The author has attempted, in this account, to discuss some of the more important factors in the production of oedema, but has tried to avoid confusing himself and the reader with too much detail.Oedema, which may be defined as a localised or generalised increase in the volume of the interstitial fluid, can arise in many diseases, and be the result of the interplay of a number of factors. These factors are not well understood - but the first patient suffered from oedema of a type where the simpler explanations would seem to suffice

SAW atomization application on inhaled pulmonary drug delivery

Pulmonary drug delivery transports the drug formulations directly to the respiratory tract in the form of inhaled particles or droplets. Because of the direct target treatment, it has significant advantages in the treatment of respiratory diseases, for example asthma. However, it is difficult to produce monodispersed particles/droplets in the 1-10 micron range, which is necessary for deposition in the targeted lung area or lower respiratory airways, in a controllable fashion. We demonstrate the use of surface acoustic waves (SAWs) as an efficient method for the generation of monodispersed micron dimension aerosols for the treatment of asthma. SAWs are ten nanometer order amplitude electroacoustic waves generated by applying an oscillating electric field to an interdigital transducer patterned on a piezoelectric substrate. The acoustic energy in the waves induces atomization of the working fluid, which contains a model drug, albuterol. Laser diffraction techniques employed to characterize the aerosols revealed mean diameter of the aerosol was around 3-4 μm. Parallel experiments employing a one-stage (glass) twin impinger as a lung model demonstrated a nearly 80% of atomized drug aerosol was deposited in the lung. The aerosol size distribution is relatively independent of the SAW frequency, which is consistent with our predictive scaling theory which accounts for the dominant balance between viscous and capillary stresses. Moreover, only 1-3 W powers consumption of SAW atomization suggests that the SAW atomizer can be miniaturized into dimensions commensurate with portable consumer device

The extraction of liquid, protein molecules and yeast cells from paper through surface acoustic wave atomization

Paper has been proposed as an inexpensive and versatile carrier for microfluidics devices with abilities well beyond simple capillary action for pregnancy tests and the like. Unlike standard microfluidics devices, extracting a fluid from the paper is a challenge and a drawback to its broader use. Here, we extract fluid from narrow paper strips using surface acoustic wave (SAW) irradiation that subsequently atomizes the extracted fluid into a monodisperse aerosol for use in mass spectroscopy, medical diagnostics, and drug delivery applications. Two protein molecules, ovalbumin and bovine serum albumin (BSA), have been preserved in paper and then extracted using atomized mist through SAW excitation; protein electrophoresis shows there is less than 1% degradation of either protein molecule in this process. Finally, a solution of live yeast cells was infused into paper, which was subsequently dried for preservation then remoistened to extract the cells via SAW atomization, yielding live cells at the completion of the process. The successful preservation and extraction of fluids, proteins and yeast cells significantly expands the usefulness of paper in microfluidics

The role of intermolecular coupling in the photophysics of disordered organic semiconductors: Aggregate emission in regioregular polythiophene

We address the role of excitonic coulping on the nature of photoexcitations in the conjugated polymer regioregular poly(3-hexylthiophene). By means of temperature-dependent absorption and photoluminescence spectroscopy, we show that optical emission is overwhelmingly dominated by weakly coupled H-aggregates. The relative absorbance of the 0-0 and 0-1 vibronic peaks provides a powerfully simple means to extract the magnitude of the intermolecular coupling energy, approximately 5 and 30 meV for films spun from isodurene and chloroform solutions respectively.Comment: 10 pages, 4 figures, published in Phys. Rev. Let

A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher PD

Correlation of the Quasi-Periodic Oscillation Frequencies of White Dwarf, Neutron Star, and Black Hole Binaries

Using data obtained in 1994 June/July with the Extreme Ultraviolet Explorer deep survey photometer and in 2001 January with the Chandra X-ray Observatory Low Energy Transmission Grating Spectrograph, we investigate the extreme-ultraviolet (EUV) and soft X-ray oscillations of the dwarf nova SS Cyg in outburst. We find quasi-periodic oscillations (QPOs) at nu_0 ~ 0.012 Hz and nu_1 ~ 0.13 Hz in the EUV flux and at nu_0 ~ 0.0090 Hz, nu_1 ~ 0.11 Hz, and possibly nu_2 ~ nu_0 + nu_1 ~ 0.12 Hz in the soft X-ray flux. These data, combined with the optical data of Woudt & Warner for VW Hyi, extend the Psaltis, Belloni, & van der Klis nu_high-nu_low correlation for neutron star and black hole low-mass X-ray binaries (LMXBs) nearly two orders of magnitude in frequency, with nu_low ~ 0.08 nu_high. This correlation identifies the high-frequency quasi-coherent oscillations (so-called ``dwarf nova oscillations'') of cataclysmic variables (CVs) with the kilohertz QPOs of LMXBs, and the low-frequency QPOs of CVs with the horizontal branch oscillations (or the broad noise component identified as such) of LMXBs. Assuming that the same mechanisms produce the QPOs in white dwarf, neutron star, and black hole binaries, we find that the data exclude the relativistic precession model and the magnetospheric and sonic-point beat-frequency models (as well as any model requiring the presence or absence of a stellar surface or magnetic field); more promising are models that interpret QPOs as manifestations of disk accretion onto any low-magnetic field compact object.Comment: 15 pages including 4 encapsulated postscript figures; LaTeX format, uses aastex.cls; accepted on 2002 July 23 for publication in The Astrophysical Journa

A hydrodynamic scheme for two-component winds from hot stars

We have developed a time-dependent two-component hydrodynamics code to simulate radiatively-driven stellar winds from hot stars. We use a time-explicit van Leer scheme to solve the hydrodynamic equations of a two-component stellar wind. Dynamical friction due to Coulomb collisions between the passive bulk plasma and the line-scattering ions is treated by a time-implicit, semi-analytic method using a polynomial fit to the Chandrasekhar function. This gives stable results despite the stiffness of the problem. This method was applied to model stars with winds that are both poorly and well-coupled. While for the former case we reproduce the mCAK solution, for the latter case our solution leads to wind decoupling.Comment: accepted to Astronomy and Astrophysic

Advanced information processing system: The Army fault tolerant architecture conceptual study. Volume 1: Army fault tolerant architecture overview

Digital computing systems needed for Army programs such as the Computer-Aided Low Altitude Helicopter Flight Program and the Armored Systems Modernization (ASM) vehicles may be characterized by high computational throughput and input/output bandwidth, hard real-time response, high reliability and availability, and maintainability, testability, and producibility requirements. In addition, such a system should be affordable to produce, procure, maintain, and upgrade. To address these needs, the Army Fault Tolerant Architecture (AFTA) is being designed and constructed under a three-year program comprised of a conceptual study, detailed design and fabrication, and demonstration and validation phases. Described here are the results of the conceptual study phase of the AFTA development. Given here is an introduction to the AFTA program, its objectives, and key elements of its technical approach. A format is designed for representing mission requirements in a manner suitable for first order AFTA sizing and analysis, followed by a discussion of the current state of mission requirements acquisition for the targeted Army missions. An overview is given of AFTA's architectural theory of operation